Spironolactone as an Adjunctive Treatment in Neovascular Age-Related Macular Degeneration
| Autor: | Jennifer Sim, Kapil G. Kapoor |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Oncology
medicine.medical_specialty genetic structures Central serous chorioretinopathy Case Report Spironolactone Mineralocorticoid receptor antagonists 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Mineralocorticoid receptor Endophthalmitis lcsh:Ophthalmology Internal medicine Age related medicine business.industry Macular degeneration medicine.disease eye diseases Eplerenone Ophthalmology Serous fluid chemistry lcsh:RE1-994 Adjunctive treatment 030221 ophthalmology & optometry sense organs business 030217 neurology & neurosurgery medicine.drug Neovascular age-related macular degeneration |
| Zdroj: | Case Reports in Ophthalmology Case Reports in Ophthalmology, Vol 8, Iss 2, Pp 314-320 (2017) |
| ISSN: | 1663-2699 |
| Popis: | Neovascular age-related macular degeneration (AMD) is a potentially sight-threatening condition. The current standard-of-care treatment regimen is serial intravitreal antivascular endothelial growth factor injections. While these typically have great success, they do carry exceptional treatment burden on the patient, cost burden due to their required frequency of use, and the risk of endophthalmitis, which can be devastating. This case report explores an alternative potential option as a treatment adjunct for neovascular AMD (nAMD), and identifies some of the overlap between nAMD and central serous chorioretionpathy. Future research is needed to better understand the role of mineralocorticoid receptor antagonist treatment in this disease spectrum. |
| Databáze: | OpenAIRE |
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