Hyperpigmentation Induced by UVB at the Application Site of Estradiol
| Autor: | J.L. Perrot, A.L. Claudy |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Melasma medicine.medical_treatment Dermatology Administration Cutaneous medicine Humans skin and connective tissue diseases Transdermal Chemotherapy Estradiol integumentary system business.industry Pruritus Middle Aged medicine.disease Hyperpigmentation Menopause Estrogen Chronic Disease Toxicity Female Ultraviolet Therapy medicine.symptom business Pigmentation Disorders Hormone |
| Zdroj: | Dermatology. 181:154-155 |
| ISSN: | 1421-9832 1018-8665 |
| DOI: | 10.1159/000247908 |
| Popis: | We report a case of a 48-year-old woman who presented with chronic essential pruritus and was successfully treated with the transdermal estradiol system because of menopausal discomfort. Suberythemogenic UVB phototherapy was proposed to the patient in order to control her pruritus. She developed hyperpigmentation at the application site of estradiol. To the best of our knowledge this is the first report suggesting a direct relationship between estrogen and melanin synthesis in humans. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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