Paediatric pulmonary echinococcosis: A neglected disease

Autor: Pierre Goussard, Ernst Eber, Lunga Mfingwana, Pieter Nel, Pawel Schubert, Jacques Janson, Richard Pitcher, Camilla le Roux
Rok vydání: 2022
Předmět:
Zdroj: Paediatric Respiratory Reviews. 43:11-23
ISSN: 1526-0542
DOI: 10.1016/j.prrv.2021.11.001
Popis: Echinococcosis is a worldwide public health problem causing considerable paediatric morbidity and mortality in endemic areas. The presentation of cystic echinococcosis (CE) varies by age. Unlike adults, where hepatic involvement is common, pulmonary CE is the dominant site in the paediatric population. Pulmonary cysts are typically first seen on chest X-ray, either as an incidental finding or following respiratory symptoms after cyst rupture or secondary infection of the cyst. In children, pulmonary cysts have a broad differential diagnosis, and a definitive diagnosis relies on the combination of imaging, serology, and histology. In countries with high infectious burdens from diseases such as acquired immunodeficiency syndrome (AIDS) and tuberculosis (TB), the diagnosis is additionally challenging, as atypical infections are more common than in developed countries. Pulmonary CE is treated with a combination of surgery and chemotherapy.
Databáze: OpenAIRE