Epidemiological and structural studies of Staphylococcus aureus R plasmids mediating resistance to tobramycin and streptogramin
| Autor: | J.M. Fouace, N. El Solh, Y.A. Chabbert, Richard P. Novick, Z. Shalita, D.H. Bouanchaud |
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| Rok vydání: | 1980 |
| Předmět: |
Serotype
Staphylococcus aureus Tetracycline R Factors Streptogramin Biology Staphylococcal Infections medicine.disease_cause Biological Evolution Virginiamycin Homology (biology) Microbiology Disease Outbreaks Restriction enzyme Plasmid medicine Tobramycin Humans France Molecular Biology medicine.drug |
| Zdroj: | Plasmid. 4(1) |
| ISSN: | 0147-619X |
| Popis: | We have studied the genetic properties of five S. aureus strains (serotypes 18 and III) isolated in France during a recent outbreak and carrying two new resistance characters (tobramycin and streptogramin). After transfer by transduction of these resistances, recipient cells were found in each case to harbor a single multicopy plasmid carrying the two resistance characters plus resistance to cadmium salts and/or resistance to tetracycline. The five Sgr-Tmr plasmids recovered by transduction are related epidemiologically; all five belong to the same incompatibility group and they share from 50 to 100% base sequence homology. Three of the five have similar restriction endonuclease patterns. |
| Databáze: | OpenAIRE |
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