Wound edge microvascular blood flow: effects of negative pressure wound therapy using gauze or polyurethane foam
| Autor: | Richard Ingemansson, Robin Martin, Malin Malmsjö, Elizabeth Mary Huddleston |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Muscle tissue
medicine.medical_specialty Swine medicine.medical_treatment Polyurethanes Microcirculation Subcutaneous Tissue Negative-pressure wound therapy Laser-Doppler Flowmetry Medicine Animals Skin Wound Healing integumentary system business.industry Blood flow Laser Doppler velocimetry Bandages Surgery Plastic surgery medicine.anatomical_structure Regional Blood Flow Wounds and Injuries business Wound healing Negative-Pressure Wound Therapy Subcutaneous tissue |
| Zdroj: | Annals of plastic surgery. 63(6) |
| ISSN: | 1536-3708 |
| Popis: | The aim of this study was to examine the effects of negative pressure wound therapy (NPWT) on wound edge microvascular blood flow, comparing different wound fillers. Wounds were created on the backs of 7 pigs. NPWT was applied, using either foam or gauze, at -50,-75, -100, -125, -150, or -175 mm Hg. Microvascular blood flow was measured in muscle tissue, subcutaneous tissue, and in the wound bed, at 0.5, 1, and 2.5 cm from the wound edge, using laser Doppler velocimetry. Similar patterns of blood flow response were observed when using foam or gauze. At 2.5 cm from the wound edge there was an increase in microvascular blood flow, while blood flow was decreased closer (0.5 cm) to the wound edge. The blood flow effects were similar at the different levels of negative pressure in muscle tissue, subcutaneous tissue, and in the wound bed. Altered microvascular blood flow to the wound edge may be one of the mechanisms by which NPWT facilitates healing. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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