Radical alkylation of para-quinone methides with 4-substituted Hantzsch esters/nitriles via organic photoredox catalysis
| Autor: | Qing-Qiang Min, Gui-Zhen Ao, Qing-Yan Wu, Feng Liu |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Organic Chemistry Visible light irradiation Photoredox catalysis Para-quinone Alkylation 010402 general chemistry 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences chemistry.chemical_compound chemistry Photocatalysis Phenols Physical and Theoretical Chemistry Alkyl |
| Zdroj: | Organicbiomolecular chemistry. 16(35) |
| ISSN: | 1477-0539 |
| Popis: | A novel photocatalytic protocol is herein described for the preparation of functionalized phenols via radical alkylation of para-quinone methides under transition-metal-free conditions. The reaction is external oxidant free and performed at ambient temperature upon visible light irradiation, allowing the access to various desired products in satisfactory yields. The readily available 4-alkyl-1,4-dihydropyridines serve as the effective alkyl radical precursors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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