Depression But Not Inflammatory Markers Are Increased in Family Versus Nonfamily Caregivers of Persons With Dementia

Autor: Aleksandra Wyczalkowska-Tomasik, Anna Sadowska, Pawel Zegarow, Bozena Czarkowska-Paczek
Rok vydání: 2020
Předmět:
Zdroj: Journal of Geriatric Psychiatry and Neurology. 34:29-36
ISSN: 1552-5708
0891-9887
DOI: 10.1177/0891988720901782
Popis: We investigated quality of life (WHOQoL-BREF), perceived stress (PSS-10), anxiety and depression (HADS-M), life satisfaction (SWLS), and serum levels of interleukin-6 (IL-6), C-reactive protein (CRP), and cortisol in family caregivers (n = 94) and professional caregivers (n = 48) of demented patients, as well as among noncaregivers (n = 30). Compared with professional caregivers, family caregivers had higher scores in HADS-M depression ( P = .003) and anxiety ( P = .033), lower life satisfaction ( P = .04), and lower quality of life in psychological ( P = .02) and social relationship ( P = .03) domains. There were no differences in serum levels of IL-6, CRP, or cortisol between caregivers and control participants. In multivariable analysis, when family relationship was considered together with the time period of caregiving and results of the Mini-Mental State Examination test in care recipients (n = 118, 12.49 ± 7.99), only family relationship influenced scores in HADS-M depression ( P = .004), SWLS scores ( P = .011), and WHOQoL-BREF scores in psychological ( P = .011) and social relationship ( P = .008) domains. In conclusion, family caregivers are more stressed and have deeper depressive and anxiety disorders, lower life satisfaction, and lower quality of life than professional caregivers.
Databáze: OpenAIRE