Early inhibition of the renin-angiotensin system improves the long-term graft survival of single pediatric donor kidneys transplanted in adult recipients

Autor:	Eric E. Simon, Rubin Zhang, Mary Killackey, Heather LaGuardia, Anil Paramesh, Brent Alper, Lotuce Lee Hamm, Katherine T. Mills, Jennifer McGee, Douglas P. Slakey
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Adult Male medicine.medical_specialty Urology Angiotensin-Converting Enzyme Inhibitors Kaplan-Meier Estimate Kidney Renin-Angiotensin System Angiotensin Receptor Antagonists Renin–angiotensin system medicine Humans Risk factor Child Retrospective Studies Transplantation Pediatric donor business.industry Incidence (epidemiology) Graft Survival Infant Middle Aged Kidney Transplantation Tissue Donors Blockade Surgery Log-rank test Proteinuria Increased risk Child Preschool Female Graft survival business
Zdroj:	Transplant International. 26
ISSN:	0934-0874
DOI:	10.1111/tri.12087
Popis:	Summary Transplanting single pediatric donor kidneys into adult recipients has an increased risk of hyperfiltration injury and graft loss. It is unknown if renin-angiotensin system (RAS) blockers are beneficial in this setting. We retrospectively analyzed 94 adults who received single kidneys from donors
Databáze:	OpenAIRE
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