Efficacy of ivermectin pour-on against Ostertagia ostertagi infection and residues in the American bison, Bison bison
| Autor: | S. M. Button, J. R. Thompson, Matthew C. Rognlie, S. E. Marley, A. Craigmill, S. Wetzlich, S. E. Knapp, T. Arndt, T. M. Stoppa |
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| Rok vydání: | 1995 |
| Předmět: |
Veterinary medicine
Administration Topical Pilot Projects Withdrawal time Biology Bison bison Feces Random Allocation Animal science Ivermectin Ostertagiasis medicine symbols.heraldic_charge Animals Parasite Egg Count Ecology Evolution Behavior and Systematics visual_art.artwork Infective stage Ostertagia ostertagi Ecology Bison Antinematodal Agents Drug Residues Adipose Tissue Liver American bison visual_art symbols Female medicine.drug |
| Zdroj: | Journal of wildlife diseases. 31(1) |
| ISSN: | 0090-3558 |
| Popis: | Sixteen American bison, Bison bison, were artificially infected with 10(5) infective stage larvae of Ostertagia ostertagi on 21 April 1993. At 42 days post-infection eight bison were treated with 0.5% ivermectin pour-on (500 micrograms/kg bodyweight) and eight treated with the carrier only. Bison were necropsied 17 and 18 days post-treatment (21 and 22 June 1993, respectively). Mean (+/- SE) of 5,413 (+/- 1,716) adults and 565 (+/- 305) immature O. ostertagi were recovered at necropsy from bison treated with the carrier. No O. ostertagi were detected in bison treated with ivermectin pour-on. Based on the levels of the ivermectin marker metabolite in liver and adipose tissue 18 days post-treatment, the established bovine withdrawal time of 48 days appears adequate to insure that violative residues do not occur. |
| Databáze: | OpenAIRE |
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