Diagnosis and Management of Alcohol Use Disorder in Patients with Liver Disease: Lights and Shadows
| Autor: | Antonio Mirijello, Giovanni Addolorato, Gabriele Angelo Vassallo, Antonio Gasbarrini |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Alcoholic liver disease Neurology medicine.medical_treatment Settore MED/12 - GASTROENTEROLOGIA Alcohol use disorder Review Liver transplantation 03 medical and health sciences Liver disease 0302 clinical medicine Intervention (counseling) medicine Secondary Prevention Humans Pharmacology (medical) Intensive care medicine Pharmacology liver transplantation business.industry Liver Diseases alcoholic cirrhosis medicine.disease psychosocial approach anti-craving drugs Substance Withdrawal Syndrome Alcoholism 030104 developmental biology Neurology (clinical) business Psychosocial 030217 neurology & neurosurgery Alcohol Abstinence alcoholic liver disease |
| Zdroj: | Neurotherapeutics |
| ISSN: | 1878-7479 |
| Popis: | Alcohol use disorder is the most common cause of advanced liver disease in the Western world. Diagnosis of alcohol use disorder can be difficult because patients with liver disease tend to deny alcohol intake for the fear of being excluded from treatment and because available biomarkers of alcohol intake have poor specificity in these patients. Alcohol abstinence is the cornerstone of the therapy in these patients. However, pharmacological treatments for alcohol use disorders have not been formally tested in patients with advanced liver disease, except for baclofen. Psychosocial intervention became crucial in these patients considering the limited pharmacological choice. However, psychosocial approach and an appropriate team to manage these patients are not still well defined. In this review, we critically discuss the diagnosis and the management of alcohol use disorder in patients with liver disease. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s13311-019-00802-8) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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