Predictors of health-related quality of life in people with amyotrophic lateral sclerosis
| Autor: | Charlotte Ytterberg, Caroline Ingre, Sverker Johansson, Marie Kierkegaard, Lotta Widén Holmqvist, Petter Sandstedt |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Coping (psychology) medicine.medical_specialty Visual analogue scale Anxiety Hospital Anxiety and Depression Scale Severity of Illness Index 03 medical and health sciences 0302 clinical medicine Interquartile range Surveys and Questionnaires Adaptation Psychological medicine Humans 030212 general & internal medicine Amyotrophic lateral sclerosis Fatigue Aged Aged 80 and over Depression Amyotrophic Lateral Sclerosis Middle Aged medicine.disease Respiration Artificial humanities Cross-Sectional Studies Mood Neurology Multivariate Analysis Quality of Life Physical therapy Female Neurology (clinical) medicine.symptom Psychology Psychosocial 030217 neurology & neurosurgery |
| Zdroj: | Journal of the Neurological Sciences. 370:269-273 |
| ISSN: | 0022-510X |
| DOI: | 10.1016/j.jns.2016.09.034 |
| Popis: | Background Knowledge of factors influencing health-related quality of life (HRQL) in people with amyotrophic lateral sclerosis (ALS) is important because some factors might be amenable to intervention. Objectives The aim was to describe and explore the effects of disease severity, fatigue, anxiety, depression, frequency of social and lifestyle activities, coping capacity and mechanical ventilator use on HRQL in people with ALS. Methods Sixty people with ALS were enrolled in this cross-sectional study. Data were collected with questionnaires during home visits. The Sickness Impact Profile and the EuroQol Visual Analogue Scale were used to assess HRQL. Multivariate regression analyses explored associations between HRQL and independent factors. Results Low frequency of social and lifestyle activities, and severe disease, were associated with worse HRQL, explaining 57% of total variance in the Sickness Impact Profile physical score. Severe disease, weak coping capacity and anxiety and/or depression were associated with worse HRQL, explaining 33% of total variance in Sickness Impact Profile psychosocial score. Fatigue and mechanical ventilator use were associated with worse HRQL, explaining 17% of variance in the EuroQol Visual Analogue Scale. Conclusion Knowledge and understanding of how frequency of social and lifestyle activities, disease severity, coping capacity, anxiety and/or depression, fatigue and ventilator use contribute to and predict self-rated HRQL can optimize person-centred care and support. |
| Databáze: | OpenAIRE |
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