Analysis of the GSTP1 rs1695 polymorphism association with the development of asthma and phenotypic manifestations
| Autor: | G. F. Mukhammadiyeva, Albina A Distanova, Alla I. Borisova, Munira M. Ziatdinova, D. O. Karimov, Yana V. Valova, Akhat B. Bakirov |
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| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
Genotype Polymorphism Single Nucleotide 03 medical and health sciences GSTP1 0302 clinical medicine Polymorphism (computer science) medicine Immunology and Allergy Humans Genetic Predisposition to Disease 030212 general & internal medicine Asthma Genetics business.industry Allergens medicine.disease Phenotype 030228 respiratory system Glutathione S-Transferase pi Case-Control Studies Pediatrics Perinatology and Child Health Polymorphic locus business Modifier Genes |
| Zdroj: | The Journal of asthma : official journal of the Association for the Care of Asthma. 59(6) |
| ISSN: | 1532-4303 |
| Popis: | The development of asthma and its related phenotypes is most likely due to the polymorphism of the so-called modifier genes. The goal of this study was to evaluate the polymorphic locus rs1695 of theThis case-control study involved 164 patients with confirmed asthma diagnosis and 147 age- and sex-matched controls. Patients were divided into two groups: with (There were no differences between patients and controls in allelic or genotype frequencies of polymorphic locus rs1695 of theThese results suggest that the carriage of the A/A genotype of polymorphic locus rs1695 of the |
| Databáze: | OpenAIRE |
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