Abuse and Misuse of Selected Dietary Supplements Among Adolescents: a Look at Poison Center Data
| Autor: | Wendy Klein-Schwartz, Jill A. Morgan, Jessica M Biggs, Omayma A. Kishk, Allison B Lardieri |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
biology
business.industry Garcinia cambogia Clinical Investigations Poison control Hypericum perforatum biology.organism_classification food.food 03 medical and health sciences 0302 clinical medicine Mood food 030225 pediatrics Environmental health Pediatrics Perinatology and Child Health Injury prevention Salvia divinorum Paullinia cupana Medicine Pharmacology (medical) 030212 general & internal medicine Adverse effect business |
| Zdroj: | The Journal of Pediatric Pharmacology and Therapeutics. 22:385-393 |
| ISSN: | 1551-6776 |
| DOI: | 10.5863/1551-6776-22.6.385 |
| Popis: | OBJECTIVE The use of dietary supplements has increased and is associated with adverse effects. Indications for use include recreation, body image concerns, mood enhancement, or control of medical conditions. The risk of adverse effects may be enhanced if agents are used improperly. The objective of this study was to determine the frequency of abuse and misuse of 4 dietary substances among adolescents reported nationally to poison centers. Secondary outcomes included an assessment of medical outcomes, clinical effects, location of treatments provided, and treatments administered. METHODS This descriptive retrospective review assessed data concerning the use of garcinia (Garcinia cambogia), guarana (Paullinia cupana), salvia (Salvia divinorum), and St John's wort (Hypericum perforatum) among adolescents reported nationally to poison centers from 2003 to 2014. Adolescents with a singlesubstance exposure to one of the substances of interest coded as intentional abuse or misuse were included. Poison center calls for drug information or those with unrelated clinical effects were excluded. Data were collected from the National Poison Data System. RESULTS There were 84 cases: 7 cases of Garcinia cambogia, 28 Paullinia cupana, 23 Salvia divinorum, and 26 Hypericum perforatum. Garcinia cambogia was used more frequently by females (100% versus 0%), and Paullinia cupana and Salvia divinorum were used more frequently by males (61% versus 36% and 91% versus 9%, respectively). Abuse, driven by Salvia divinorum, was more common overall than misuse. Abuse was also more common among males than females (p CONCLUSIONS Abuse and misuse of these dietary supplements was uncommon, and outcomes were mild. Further research should be performed to determine use and outcomes of abuse/misuse of other dietary supplements in this population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|