Benefits of Continuous Positive Airway Pressure (CPAP) During Radiation Therapy: A Prospective Trial
| Autor: | Yaacov Richard Lawrence, Sarit Appel, Zvi Symon, Galia Jacobson, Orit Kaidar-Person, Merav Akiva Ben-David, Ilana Weiss, Maoz Ben Ayun, Noam Weizman, N. Peled, Shira Galper, Jeffrey Goldstein |
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| Přispěvatelé: | RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Radiotherapie |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Cancer Research Lung Neoplasms MOTION medicine.medical_treatment Computed tomography 030218 nuclear medicine & medical imaging 0302 clinical medicine TUMOR Lung volumes Organ Motion Continuous positive airway pressure Prospective Studies Tumor motion Aged 80 and over Radiation STEREOTACTIC ABLATIVE RADIOTHERAPY medicine.diagnostic_test Continuous Positive Airway Pressure Respiration Liver Neoplasms Heart Middle Aged medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Female Radiology Lung Volume Measurements Adult medicine.medical_specialty 03 medical and health sciences DELIVERY Breast cancer Imaging Three-Dimensional medicine Unilateral Breast Neoplasms MANAGEMENT Humans Radiology Nuclear Medicine and imaging Four-Dimensional Computed Tomography Aged Lung business.industry medicine.disease respiratory tract diseases Radiation therapy Radiation Pneumonitis Prospective trial business Tomography X-Ray Computed LUNG |
| Zdroj: | International Journal of Radiation Oncology Biology Physics, 110(5), 1466-1472. Elsevier Science |
| ISSN: | 0360-3016 |
| Popis: | Purpose: This study aimed to study the impact of continuous positive airway pressure (CPAP) on chest anatomy and tumor motion in patients receiving radiation therapy.Methods and Materials: Patients with primary or secondary lung tumors, left-sided breast cancer, or liver metastases referred for radiation therapy were trained to breathe with a CPAP device using a face mask to a maximal pressure of 15 cm H2O. Three- and 4-dimensional computed tomography simulation was performed twice for each patient: once with free breathing (FB) and again using CPAP. Volumetric and dosimetric parameters of treatment plans were compared.Results: Forty-nine patients were enrolled, of whom 6 withdrew consent before simulation and 3 withdrew because of discomfort. Thus, a total of 40 patients were analyzed. Twenty-seven patients (67.5%) were treated with CPAP based on confirmation of the volumetric or dosimetric benefit of CPAP. Mean lung volume increased by 37% (P |
| Databáze: | OpenAIRE |
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