Fruit–pollen–latex cross‐reactivity: implication of profilin (Bet v 2)
| Autor: | C Sánchez-Fernández, M L Díez-Gómez, Santiago Quirce, A Martínez, G Baz, F J Moradiellos, Manuela Cuevas |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male Allergy Latex Hypersensitivity Adolescent Immunoblotting Immunology chemical and pharmacologic phenomena Cross Reactions medicine.disease_cause Immunoglobulin E Cross-reactivity Trees Epitopes Profilins Allergen Mugwort Contractile Proteins Pollen medicine Hypersensitivity Humans Immunology and Allergy Skin Tests biology Chemistry Microfilament Proteins food and beverages hemic and immune systems Aeroallergen Middle Aged medicine.disease Recombinant Proteins Fruit biology.protein Female Food Hypersensitivity |
| Zdroj: | Allergy. 54:951-961 |
| ISSN: | 1398-9995 0105-4538 |
| DOI: | 10.1111/j.1398-9995.1999.tb00003.x |
| Popis: | Background: An association between allergy to fruits and latex, and between pollen and plant-derived food has been described. The cross-reactive structures responsible for these associations have not yet been completely elucidated. Methods: IgE reactivity to the recombinant allergens Bet v 1 and Bet v 2, different pollens, natural latex, papain, and bromelain was investigated in 29 patients with allergy to fruits or vegetables who lived in an area without birch trees. Results: Exactly 79.3% of patients were allergic to grass pollen, and two of them had clinical allergy to latex. Serum IgE reactivity (CAP) to birch pollen was found in 65% of patients, to Bet v 2 in 51.7%, to Bet v 1 in 3.4%, to latex in 58.6%, to bromelain in 51.7%, and to papain in 17.2% of patients. All subjects with positive IgE to Bet v 2 had also reactivity to latex, grass, olive tree, birch, and mugwort pollens. The six patients not allergic to pollen did not show IgE reactivity to latex, Bet v 1, or Bet v 2. A significant correlation was found between CAP to latex with Bet v 2 (r=0.86, P |
| Databáze: | OpenAIRE |
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