Mycoplasma pneumoniae pneumonia following assisted ventilation
| Autor: | Catherine Guidon-Attali, Jean Paul Casalta, Marc Alazia, Philippe Piquet, Didier Raoult, Michel Drancourt |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Molecular Sequence Data Hypoxemia Serology Internal medicine Pneumonia Mycoplasma medicine Humans Aged Mechanical ventilation Cross Infection biology Base Sequence business.industry Outbreak General Medicine Perioperative Vascular surgery Middle Aged medicine.disease Respiration Artificial respiratory tract diseases Surgery Mycoplasma pneumoniae Pneumonia Immunoglobulin M biology.protein medicine.symptom business |
| Zdroj: | The American journal of medicine. 101(2) |
| ISSN: | 0002-9343 |
| Popis: | BACKGROUND: Mycoplasma pneumoniae pneumonia is regarded as a community-acquired pneumonia, rarely requiring hospitalization, with sporadic cases or limited outbreaks occurring after close contacts with an infected patient. Few reports mention M pneumoniae pneumonia acquired during hospitalization. PATIENTS AND METHODS: M pneumoniae was diagnosed in patients who developed pneumonia following perioperative and postoperative assisted ventilation by the isolation of M pneumoniae from bronchial washing, the detection of M pneumoniae DNA from bronchial washing, and serologic testing for the presence of specific immunoglobulin M (IgM) antibodies. RESULTS: Four patients were diagnosed as having M pneumoniae pneumonia following mechanical ventilation over a 1/2-year period. They were men, older than 50 years, and were hospitalized for vascular surgery. They developed febrile hypoxemia and intersticial pneumonia. Isolation of M pneumoniae and detection of M pneumoniae DNA were positive in 1 case; specific IgM antibodies were present in 4 cases. CONCLUSIONS: These observations allow the description of a new clinical entity and highlight the role of M pneumoniae as an agent of nosocomial infections. This diagnosis should be considered in any patient with precocious post-assisted ventilation febrile hypoxemia and diffuse interstitial pneumonia, and empiric treatment protocols may include M pneumoniae in their spectrum. |
| Databáze: | OpenAIRE |
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