Germ cell tumors of the sacrococcygeal region: radiologic-pathologic correlation
| Autor: | J L Buck, P J Keslar, E S Suarez |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Male
endocrine system Pathology medicine.medical_specialty endocrine system diseases urologic and male genital diseases Coccygectomy Ultrasonography Prenatal Diagnosis Differential Pregnancy Prenatal Diagnosis medicine Humans Radiology Nuclear Medicine and imaging Child neoplasms Germinoma Ossification business.industry Sacrococcygeal Region Endodermal Sinus Tumor Infant Newborn Teratoma medicine.disease Endodermal sinus tumor Magnetic Resonance Imaging female genital diseases and pregnancy complications Fetal Diseases Child Preschool Female Germ cell tumors medicine.symptom business Tomography X-Ray Computed Calcification |
| Zdroj: | Radiographics : a review publication of the Radiological Society of North America, Inc. 14(3) |
| ISSN: | 0271-5333 |
| Popis: | Germ cell tumors of the sacrococcygeal region include mature and immature teratomas and endodermal sinus tumor. Most sacrococcygeal teratomas are discovered in the newborn period as an obvious mass, but they may be detected prenatally. Endodermal sinus tumors are usually discovered later in early childhood. Pathologically and radiologically, teratomas are either both cystic and solid, predominantly cystic, or rarely solid. Over 50% have calcification or ossification. Most malignant teratomas have substantial solid components and may contain calcification. Treatment is surgical excision including coccygectomy. Malignant tumors are treated with both surgery and chemotherapy. Prognosis is excellent for teratoma, although local recurrences may occur. Malignant teratomas have had a dismal prognosis in the past, which has been improved with multiagent chemotherapy. |
| Databáze: | OpenAIRE |
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