Interrogation of cancer gene dependencies reveals novel paralog interactions of autosome and sex chromosome encoded genes

Autor: Popa, Alexandra, Thatikonda, Venu, Köferle, Anna, Mair, Barbara, Neumüller, Ralph, Schlattl, Andreas
Rok vydání: 2022
DOI: 10.6084/m9.figshare.17212355
Popis: We systematically searched for cancer-relevant paralog interactions using CRISPR screens and publicly available loss-of-function datasets. Our analysis revealed >2,000 candidate dependencies.
Databáze: OpenAIRE