Thermal and metabolic factors affecting bioaccumulation of triazine herbicides by rainbow trout (Oncorhynchus mykiss)
| Autor: | Nakari Tarja, Luotola Marja, Ennola Kari, Erkomaa Kirsti |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Health
Toxicology and Mutagenesis Management Monitoring Policy and Law Toxicology chemistry.chemical_compound Detoxification Cytochrome P-450 CYP1A1 Animals Ecotoxicology Glucuronosyltransferase Salmonidae biology Herbicides Triazines Temperature General Medicine Terbuthylazine Pesticide biology.organism_classification Liver chemistry Oncorhynchus mykiss Bioaccumulation Environmental chemistry Inactivation Metabolic Toxicity Rainbow trout Water Pollutants Chemical |
| Zdroj: | Environmental Toxicology. 18:219-226 |
| ISSN: | 1522-7278 1520-4081 |
| DOI: | 10.1002/tox.10118 |
| Popis: | The bioaccumulation of the triazine herbicides terbutryn and terbuthylazine in rainbow trout was investigated at water temperatures of 4°C, 10°C, and 17°C. The synergetic effect of water temperature and herbicide on fish liver detoxification metabolism was also studied by measuring liver ethoxyresorufin-O-deethylase (EROD) and UDP-glucuronosyltransferase (UDPGT) activities. The bioaccumulation of terbutryn increased significantly with increasing water temperature. However, temperature seemed to have no effect on the bioaccumulation of terbuthylazine. Both chemicals decreased the measured enzyme activities. Also, temperature effects were significant. In all tests the highest liver EROD activities were measured in fish exposed to a water temperature of 4°C, and the activities decreased with increasing water temperature. The thermal effects on fish liver UDPGT activity differed between the herbicides. The highest activities at a water temperature of 4°C were measured in fish exposed to terbutryn, whereas fish exposed to terbuthylazine had the highest liver UDPGT activities at 17°C. Measuring liver detoxification metabolism together with bioaccumulation increases the understanding of bioaccumulation of chemicals in different environmental conditions. © 2003 Wiley Periodicals, Inc. Environ Toxicol 18: 219–226, 2003. |
| Databáze: | OpenAIRE |
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