Laparoscopic Pediatric Inguinal Hernia Repair: A Pilot Study in a Novel Guinea Pig Animal Model
| Autor: | Michael V. Tirabassi, Kaitlyn E. Wong, Maria Carmen Mora, Katharine R. Bittner, Kevin P. Moriarty, David B. Tashjian |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Guinea Pigs Hernia Inguinal Pilot Projects 03 medical and health sciences Random Allocation 0302 clinical medicine Postoperative Complications Suture (anatomy) medicine Animals Humans Hernia Laparoscopy Child Herniorrhaphy Wound Healing Chi-Square Distribution medicine.diagnostic_test Sutures business.industry Perioperative medicine.disease Hernia repair Surgery Inguinal hernia Dissection Disease Models Animal Treatment Outcome 030220 oncology & carcinogenesis Anesthesia 030211 gastroenterology & hepatology Ligation business |
| Zdroj: | Journal of laparoendoscopicadvanced surgical techniques. Part A. 27(6) |
| ISSN: | 1557-9034 |
| Popis: | The purpose of this study was to compare different techniques for pediatric laparoscopic inguinal hernia repair. We hypothesize that the amount of dissection performed at the internal ring, with or without division of the peritoneum, will impact healing and thus long-term success of the repair.Following the Institution's Animal Care and Use Committee approval (708024-4), 20 Hartley guinea pigs underwent laparoscopic repair of their natural open internal rings. The guinea pigs were divided equally into four surgical groups: intracorporeal suture repair (IS), hernia dissection and division with intracorporeal suture (DDIS) repair, subcutaneous endoscopically assisted ligation (SEAL), and Yueng (HOOK) repair. After a 6-week survival period, a necropsy was performed. Repairs were evaluated and tested under pressures up to 30 mmHg. The suture was then removed to assess primary healing. Experimental data were analyzed using chi-square test.There were no perioperative or postoperative complications. On initial evaluation, before suture removal, repair integrity was as follows: 5/10 IS, 10/10 DDIS, 7/10 SEAL, and 7/10 HOOK (P = .09). After suture removal, repair integrity was as follows: 3/10 IS, 10/10 DDIS, 5/10 SEAL, and 6/10 HOOK (P = .01).Overall, dissecting and dividing the sac with intracorporeal suture (DDIS) closure had the best outcome. This method appears to best replicate standard open high ligation. |
| Databáze: | OpenAIRE |
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