Precision of regional wall motion estimates from ultra-low-dose cardiac CT using SQUEEZ
| Autor: | Noemie Keller, Elliot R. McVeigh, Amir Pourmorteza, Henry R. Halperin, Marcus Y. Chen, Richard J. Chen, Albert C. Lardo |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Cardiac function curve
Image quality Computed Tomography Angiography Swine Myocardial Infarction 030204 cardiovascular system & hematology Anterior Descending Coronary Artery Signal-To-Noise Ratio Coronary Angiography Radiation Dosage Article 030218 nuclear medicine & medical imaging 03 medical and health sciences Ventricular Dysfunction Left 0302 clinical medicine Occlusion medicine Animals Radiology Nuclear Medicine and imaging Cardiac imaging Ejection fraction Radon transform business.industry Models Cardiovascular Radiation Exposure Image Enhancement Disease Models Animal medicine.anatomical_structure Ventricle Chronic Disease Radiographic Image Interpretation Computer-Assisted Female Cardiology and Cardiovascular Medicine business Nuclear medicine Endocardium |
| Zdroj: | The international journal of cardiovascular imaging. 34(8) |
| ISSN: | 1875-8312 |
| Popis: | PURPOSE: Resting regional wall motion abnormality (RWMA) has significant prognostic value beyond the findings of computed tomography (CT) coronary angiography. Stretch quantification of endocardial engraved zones (SQUEEZ) has been proposed as a measure of regional cardiac function. The purpose of the work reported here was to determine the effect of lowering the radiation dose on the precision of automatic SQUEEZ assessments of RWMA. METHODS: Chronic myocardial infarction (MI) was created by a two-hour occlusion of the left anterior descending coronary artery in 10 swine (heart rates 80–100, Ejection Fraction 25%–57%). CT was performed 5–11 months post infarct using first-pass contrast enhanced segmented cardiac function scans on a 320-detector row scanner at 80 kVp / 500 mA. Images were reconstructed at end diastole and end systole with both filtered back projection and using the “standard” Adaptive Iterative Dose Reduction (AIDR) algorithm. For each acquisition, 9 lower dose acquisitions were created. End systolic myocardial function maps were calculated using SQUEEZ for all noise levels and contrast-to-noise ratio (CNR) between the left ventricle blood and myocardium was calculated as a measure of image quality. RESULTS: For acquisitions with CNR>4, SQUEEZ could be estimated with a precision of ±0.04 (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink