Biological activities and metabolism of the lysophosphoinositides and glycerophosphoinositols
| Autor: | Christopher P. Berrie, Daniela Corda, Cristiano Iurisci |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Phospholipase A
Cell Lysophospholipids Cell Biology Metabolism Glycerophospholipids Biology Phosphatidylinositols Models Biological GTP Phosphohydrolases Cell biology chemistry.chemical_compound Phospholipase A2 medicine.anatomical_structure chemistry Biochemistry Phospholipid homeostasis biology.protein medicine Animals Humans lipids (amino acids peptides and proteins) Arachidonic acid Molecular Biology |
| Zdroj: | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1582:52-69 |
| ISSN: | 1388-1981 |
| DOI: | 10.1016/s1388-1981(02)00137-3 |
| Popis: | The lysophospholipids are integral components of the plasma membrane that have often been considered as side products of the phospholipase A2 (PLA2)-dependent production of arachidonic acid and the deacylation/reacylation processes involved in phospholipid homeostasis. Data indicating roles of these lipid derivatives in hormone responses and cell transformation have now led to a different view, and the understanding of their involvement in the modulation of cell function is building up. Here, we will summarise the current knowledge concerning the biological roles of the lysophosphoinositides and the glycerophosphoinositols (their fully deacylated counterparts) in the framework of their known effects, and those of the other lysophospholipids and glycerophospholipids. |
| Databáze: | OpenAIRE |
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