| Autor: |
Luiz Felipe, Palma, Marcelo, Marcucci, Cíntia Maria, Remondes, Leandro, Chambrone |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
National Journal of Maxillofacial Surgery. 12:333 |
| ISSN: |
0975-5950 |
| DOI: |
10.4103/njms.njms_413_21 |
| Popis: |
One of the most important complications of radiotherapy (RT) for head-and-neck cancer (HNC) is osteoradionecrosis (ORN) of the jaws, which mostly arises from tooth extractions. The ORN treatment still represents a great challenge; therefore, the prevention is of paramount importance. Thus, the present study aimed to evaluate retrospectively a perioperative systemic antibiotic therapy protocol for the prevention of ORN following tooth extraction in head-and-neck patients post-3D conformal RT.A retrospective medical record review was performed considering HNC patients submitted to RT in the period between 2008 and 2019. They necessarily received oral antibiotic therapy with Clindamycin 300 mg every 8 h for 10 days, with the first dose 3 days before the tooth extraction.Forty-nine patients met the study criteria, with a total of 107 teeth extracted. Regarding the 47 patients who did not develop ORN, 103 tooth extractions were identified (96.3%). Only two patients developed ORN at two adjacent teeth sites (3.7%).The proposed perioperative systemic antibiotic therapy protocol seems to be efficient to prevent ORN following tooth extraction in postirradiated HNC patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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