Intraoperative Scrape Cytology from Ovarian Masss Lesions: A Study of 81 Cases
| Autor: | Shyama Jain, Jenna Blah Bhattacharya, Meeta Singh, Amita Jain Gupta, S Anusha, Nita Khurana |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Pathology endocrine system Histology Frozen section 030209 endocrinology & metabolism ovarian mass lesions scrape smears Pathology and Forensic Medicine Metastasis 03 medical and health sciences 0302 clinical medicine medicine Cyst lcsh:QH573-671 Pathological Frozen section procedure business.industry lcsh:Cytology medicine.disease Serous fluid intraoperative cytology 030220 oncology & carcinogenesis Histopathology Original Article Teratoma Fibroma business |
| Zdroj: | Journal of Cytology, Vol 36, Iss 3, Pp 174-179 (2019) Journal of Cytology |
| ISSN: | 0970-9371 |
| Popis: | Background: Intraoperative evaluation of an ovarian mass is of crucial importance in its further management, accomplished by frozen section (FS) and scrape smear (SS) examination. Aim: To evaluate utility of SS over FS and to study scrape cytological features of a variety of ovarian neoplasms. Materials and Methods: The study comprised ovarian tumors studied over a period of 1 year (2014–2015) that were submitted for intraoperative assessment. SS and FS were examined and evaluated independently. The results were compared with final pathological diagnosis in each case, and cases with discordant diagnoses were reviewed. All the SSs of ovarian tumors were re-evaluated with Giemsa-stained smears, and cytological features were described. Results: The results of SS and FS were 100% concordant. On histopathology, of 81 cases, 43 were epithelial [(categorized further as serous, mucinous, or malignant mixed Mullerian tumor (MMMT)] along with subcategorization of benign, borderline, and malignant), 16 were germ cell (categorized as teratoma: mature/immature and yolk sac tumor), 11 were sex cord stromal tumors (fibroma, granulosa cell tumor, Sertoli–Leydig cell tumor), 8 cases were hemorrhagic cysts (torsion, endometroid, corpus luteal cyst, etc.), and 3 were metastasis. There were 61 benign, 2 borderline, and 18 malignant cases on FS and scrape. Combining all the values, sensitivity and specificity were 76% and 98.21%, respectively. The diagnostic accuracy in diagnosing malignant lesions was 91%. Conclusion: Adequate knowledge on cytohistological correlation of ovarian scrape cytology may phase out the use of cryostat in intraoperative diagnosis of ovarian neoplasms, and thus be a boon for resource-deprived settings. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
| Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |