Cyclophilin a plays distinct roles in human immunodeficiency virus type 1 entry and postentry events, as revealed by spinoculation

Autor:	Andrew C. S. Saphire, Philippe Gallay, Michael Bobardt
Rok vydání:	2002
Předmět:	biology Immunology Human immunodeficiency virus (HIV) Replication Cypa Centrifugation Enzyme-Linked Immunosorbent Assay biology.organism_classification medicine.disease_cause Microbiology Virology Cyclophilin A Insect Science medicine HIV-1 Humans HeLa Cells Polysaccharide-Lyases
Zdroj:	Journal of virology. 76(9)
ISSN:	0022-538X
Popis:	Cyclophilin A (CypA) is necessary for effective human immunodeficiency virus type 1 (HIV-1) replication. However, the functions of CypA and the precise steps at which CypA acts in the HIV-1 life cycle remain to be determined. By using a methodology that bypasses the need for attachment factors—spinoculation—we present evidence that CypA participates in both entry and postentry events.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7757a5feec54ad7507171df9edc42405 https://pubmed.ncbi.nlm.nih.gov/11932436 Zobrazit plný text záznamu