Real-world data on diffuse large B-cell lymphoma in 2010–2019: usability of large data sets of Finnish hospital data lakes

Autor:	Samuli Tuominen, Kristiina Uusi-Rauva, Tea Blom, Sirkku Jyrkkiö, Kaisa Tuppurainen, Erika Alanne
Rok vydání:	2022
Předmět:	Aged 80 and over Male Cancer Research Antineoplastic Agents General Medicine Middle Aged Survival Analysis Hospitals Oncology Electronic Health Records Humans Female Lymphoma Large B-Cell Diffuse Registries Algorithms Finland Aged Retrospective Studies
Zdroj:	Future Oncology. 18:1103-1114
ISSN:	1744-8301 1479-6694
Popis:	Background: Real-world data on diffuse large B-cell lymphoma (DLBCL) has remained incomplete. In Finland, health record data originally recorded in different hospital data record systems are collectively available via data lake technology, enabling efficient extraction and analysis of large data sets. The usability of Finnish data lake data in the assessment of DLBCL was evaluated. Methods: Adult DLBCL patients diagnosed between 2010 and 2019, home municipality in the Hospital District of Southwest Finland and data available in respective data lake were included. Results: The algorithmic determination of treatment lines and respective survival was successful. Patient characterization was feasible, albeit partly incomplete because of limited data content/availability and coverage. Stage, International Prognostic Index and cell of origin were available for 63.0, 68.3 and 28.4% of patients, respectively. Genetic aberrations were not structurally available or feasible to extract without a manual chart review. Conclusion: Finnish data lakes represent an efficient way to analyze large DLBCL data sets. The current study provides a tool for developing recording practices in routine care.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7756b87bacca974659d5d454cf196a60 https://doi.org/10.2217/fon-2021-0806 Zobrazit plný text záznamu