Risk of lymph node metastasis in early gastric cancer and indications for endoscopic resection: is it worth applying the east rules to the west?
| Autor: | Jales Benevides Santana Filho, Leonardo Medeiros Milhomem, Alan Kagan, Eliane Duarte Mota, Orlando Milhomem da Mota, Daniela Medeiros Milhomem-Cardoso |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Endoscopic Mucosal Resection Lymphovascular invasion medicine.medical_treatment Gastroenterology Gastrectomy Risk Factors Stomach Neoplasms Internal medicine medicine Humans Neoplasm Invasiveness Retrospective Studies Univariate analysis business.industry Retrospective cohort study Hepatology Early Gastric Cancer Gastric Mucosa Lymphatic Metastasis Cohort Lymph Node Excision Surgery business Abdominal surgery |
| Zdroj: | Surgical Endoscopy. 35:4380-4388 |
| ISSN: | 1432-2218 0930-2794 |
| Popis: | Early gastric cancers are associated with lymph node metastasis (LNM) in 15% of cases. Risk factors for LNM are well established in Eastern countries. Less invasive treatments, such as endoscopic or surgical laparoscopic resection, are well accepted in Eastern countries and a matter of intense debate in the West, were indications for such treatments are still contested The objective of the study is to determine risk factors related to LNM and to validate endoscopic resection indications. The study was a retrospective cohort of 178 patients with early gastric cancer who underwent gastrectomy. Clinical and pathological factors were analyzed. The new rules of ER from JGCA were applied to the studied cohort. LNM was present in 13.48% of the cases, 3.96% (3/76) in T1a tumors and 20.58% (21/102) in T1b tumors. In univariate analysis ulceration (p = 0.04), differentiation grade (p = 0.04), submucosal invasion (p = 0.001), lymphatic invasion (p |
| Databáze: | OpenAIRE |
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