Gold nanoparticles designed for combining dual modality imaging and radiotherapy
| Autor: | Pascal Perriat, Géraldine Le Duc, Stéphane Roux, Alice Le Meur-Herland, Raphaël Serduc, Claire Billotey, Christophe Alric, Olivier Tillement, Céline A. Mandon, Jacqueline Taleb |
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| Přispěvatelé: | Matériaux, ingénierie et science [Villeurbanne] (MATEIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Mateis, Laboratoire |
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Biodistribution
Materials science Gadolinium medicine.medical_treatment chemistry.chemical_element 02 engineering and technology [SPI.MAT] Engineering Sciences [physics]/Materials 010402 general chemistry 01 natural sciences [SPI.MAT]Engineering Sciences [physics]/Materials Inorganic Chemistry Nuclear magnetic resonance Materials Science(all) Metallic materials medicine General Materials Science Gold core ComputingMilieux_MISCELLANEOUS medicine.diagnostic_test Magnetic resonance imaging 021001 nanoscience & nanotechnology 0104 chemical sciences Radiation therapy chemistry Colloidal gold Dual modality 0210 nano-technology |
| Zdroj: | Gold Bulletin : The journal of gold science, technology and applications Gold Bulletin : The journal of gold science, technology and applications, Springer, 2008, pp.90-97 |
| ISSN: | 2364-821X 2190-7579 |
| Popis: | The synthesis of gold nanoparticles functionalized by gadolinium chelates constitutes an attractive way for combining imaging and therapy. The presence of gadolinium chelates allows monitoring their biodistribution after intravenous injection in small animals by magnetic resonance imaging (MRI) while the gold core strongly absorbs the X-ray photons. This feature is exploited for X-ray imaging but also for radiotherapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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