Drosophila melanogaster as a model for nutrient regulation of ovarian function
| Autor: | Alissa R. Armstrong |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Embryology 030219 obstetrics & reproductive medicine biology Dietary control Obstetrics and Gynecology Nutritional status Cell Biology biology.organism_classification Oogenesis 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Endocrinology Nutrient Ovarian function Reproductive Medicine Evolutionary biology Drosophila melanogaster Drosophila Organism |
| Zdroj: | Reproduction. 159:R69-R82 |
| ISSN: | 1741-7899 1470-1626 |
| DOI: | 10.1530/rep-18-0593 |
| Popis: | Observed in a wide variety of organism, from invertebrates to mammals, nutritional status modulates the energetically costly effort of producing female gametes. Despite this long-standing link between nutrition and ovarian function, relatively little is known about the cellular and molecular mechanisms that underlie how dietary components modulate egg production. Drosophila melanogaster, with its powerful and extensive genetic tools as well as its well-characterized ovarian response to diet, has proven to be instrumental in addressing this issue. This review covers what we currently know about the dietary control of oogenesis in Drosophila and the salient features of the fruit fly that make it a model for nutritional control of ovarian function. |
| Databáze: | OpenAIRE |
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