Bilateral central retina vein occlusion associated with obesity-hypoventilation syndrome (pickwickian syndrome)

Autor: Hugo Quiroz-Mercado, Adai Perez-Montesinos, C. Gonzalez-Mijares, Raul Velez-Montoya, Mauricio Turati, Gerardo Garcia-Aguirre
Rok vydání: 2014
Předmět:
Zdroj: Retinal casesbrief reports. 3(2)
ISSN: 1935-1089
Popis: Purpose: To describe bilateral central retinal vein occlusion (CRVO) as a clinical manifestation of obesity–hypoventilation syndrome (pickwickian syndrome). Method: Case report. Patient: A 37-year-old Hispanic man with morbid obesity and obstructive sleep apnea who suddenly developed bilateral loss of vision. Results: Laboratory studies disclosed the following: hematocrit, 81%; body mass index, 55 kg/m2; PaCO2, 52 mmHg; and blood oxygen saturation (SaO2), 54%. Polysomnography demonstrated 45 obstructive apneas and 133 obstructive hypopneas, with abnormal movements of the inferior limbs during sleep. Discussion: Hypoxia and hypercapnia produce severe erythrocytosis that causes a change in blood viscosity. This may facilitate thrombus formation at the lamina cribrosa of both eyes manifested as bilateral CRVO.
Databáze: OpenAIRE