A Nosocomial Outbreak of Invasive Listeriosis in An Italian Hospital: Epidemiological and Genomic Features
| Autor: | Teresa Bossù, Stefano Bilei, Valeria Russini, Anna Giovanna Fermani, Giovanni Blanco, Gina Di Giampietro, Roberta Parisella, Sergio Parrocchia, Paolo Fabietti, Martina Spaziante, Maria Laura De Marchis, Riccardo Marrone, Tiziana Zottola |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
ST451 medicine.medical_specialty Disease medicine.disease_cause Article Opportunistic pathogen Listeria monocytogenes listeriosis Environmental health Epidemiology medicine Immunology and Allergy Molecular Biology Nosocomial outbreak whole genome sequencing General Immunology and Microbiology business.industry Public health Outbreak nosocomial outbreak Infectious Diseases Medicine Invasive Listeriosis business |
| Zdroj: | Pathogens Volume 10 Issue 5 Pathogens, Vol 10, Iss 591, p 591 (2021) |
| ISSN: | 2076-0817 |
| DOI: | 10.3390/pathogens10050591 |
| Popis: | Listeria monocytogenes (L. monocytogenes) is a widespread opportunistic pathogen that causes the listeriosis foodborne disease. This bacterium has become a common contaminant of handled food, and a relevant public health issue. Here we describe a nosocomial outbreak of listeriosis caused by an ST451 strain of L. monocytogenes involving three cancer and one immunocompromised patients hospitalized in different units from the same hospital during September and October 2020. The epidemiological investigation was conducted using traditional microbiological methodology combined with a whole genome sequencing approach. The source of contamination was identified in the kitchen hospital, where a meat slicer used to prepare patients’ meals was tested positive to the same sequence type (ST) of L. monocytogenes. This is the first report of an outbreak of listeriosis caused by ST451 in Italy. |
| Databáze: | OpenAIRE |
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