Preterm delivery and exposure to active and passive smoking during pregnancy: a case?control study from Italy
| Autor: | Guglielmina Fantuzzi, Fabio Facchinetti, Fabio Barbone, Gabriella Aggazzotti, S. Kanitz, Salvatore Sciacca, Elena Righi, V. Leoni, Leila Fabiani, Maria Triassi, Emma Bertucci, Mario Alberto Battaglia, Giuliano Sansebastiano |
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| Přispěvatelé: | Fantuzzi, G, Aggazzotti, G, Righi, E, Facchinetti, F, Bertucci, E, Kanitz, S, Barbone, F, Sansebastiano, G, Battaglia, Ma, Leoni, V, Fabiani, L, Sciacca, S, Triassi, Maria |
| Rok vydání: | 2007 |
| Předmět: |
environmental tobacco smoke
maternal smoking preterm delivery Adult Male Pediatrics medicine.medical_specialty Passive smoking Epidemiology case-control study Logistic regression medicine.disease_cause Tobacco smoke Pregnancy Risk Factors Prevalence Humans Preterm delivery Medicine business.industry Smoking Confounding Infant Newborn Case-control study medicine.disease Italy exposure to active and passive smoking Maternal Exposure Case-Control Studies Pediatrics Perinatology and Child Health Premature Birth Gestation Female Tobacco Smoke Pollution business |
| Zdroj: | Paediatric and Perinatal Epidemiology. 21:194-200 |
| ISSN: | 1365-3016 0269-5022 |
| DOI: | 10.1111/j.1365-3016.2007.00815.x |
| Popis: | The aim of this study was to assess the relationship between preterm/early preterm delivery and active smoking as well as environmental tobacco smoke (ETS) exposure in a sample of pregnant Italian women. A case-control study was conducted in nine cities in Italy between October 1999 and September 2000. Cases of preterm birth were singleton babies born before the 37th gestational week; babies born before the 35th gestational week were considered early preterm births. Controls were babies with gestational ages >or= 37th week. A total of 299 preterm cases (including 105 early preterm) and 855 controls were analysed. A self-administered questionnaire was used to assess active smoking and ETS exposure, as well as potential confounders. Multivariable logistic regression analysis showed a relationship between active smoking during pregnancy and preterm/early preterm delivery [adjusted ORs: 1.53; 95% CI 1.05, 2.21 and 2.00; 95% CI 1.16, 3.45, respectively]. A dose-response relationship was found for the number of cigarettes smoked daily. The adjusted ORs were 1.54 and 1.69 for preterm babies and 1.90 and 2.46 for early preterm babies for 1-10 and >10 cigarettes/day respectively. ETS exposure was associated with early preterm delivery [adjusted OR 1.56; 95% CI 0.99, 2.46] with a dose-response relationship with the number of smokers in the home. Smoking during pregnancy was strongly associated with preterm delivery with a dose-response effect. ETS exposure in non-smoking women was associated only with early preterm delivery. |
| Databáze: | OpenAIRE |
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