Burgeoning study of sentinel-node analysis on management of early gastric cancer after endoscopic submucosal dissection
| Autor: | Xiaocen Zhang, Stavros N. Stavropoulos, David Friedel |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Malignancy 03 medical and health sciences 0302 clinical medicine Breast cancer medicine Lymph node Early gastric cancer Function-preserving gastrectomy Organ preserving surgery business.industry Sentinel node navigation surgery Minireviews Lymphadenectomy Sentinel node Endoscopic submucosal dissection medicine.disease Early Gastric Cancer Dissection medicine.anatomical_structure 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Gastrectomy Radiology business Expanded criteria |
| Zdroj: | World Journal of Gastrointestinal Endoscopy |
| ISSN: | 1948-5190 |
| Popis: | Endoscopic submucosal dissection (ESD) represents an organ-preserving alternative to surgical resection of early gastric cancer. However, even with ESD yielding en-bloc resection specimens, there are concerns regarding tumor spread such as with larger lesions, ulcerated lesions, undifferentiated pathology and submucosal invasion. Sentinel node navigational surgery (SNNS) when combined with ESD offers a minimally invasive alternative to the traditional extended gastrectomy and lymphadenectomy if lack of lymph node spread can be confirmed. This would have a clear advantage in terms of potential complications and quality of life. However, SNNS, though useful in other malignancies such as breast cancer and melanoma, may not have a sufficient sensitivity for malignancy and negative predictive value in EGC to justify this as standard practice after ESD. The results of SNNS may improve with greater standardization and more involved dissection, technological innovations and more experience and validation such that the paradigm for post-ESD resection of EGC may change and include SNNS. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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