Nanosystems Applied to HIV Infection: Prevention and Treatments
| Autor: | Francisco N. Figueroa, María Ángeles Muñoz-Fernández, Dariana Aristizabal Bedoya, Micaela A. Macchione, Miriam Cristina Strumia |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Human immunodeficiency virus (HIV) Review 02 engineering and technology medicine.disease_cause nanosystems lcsh:Chemistry prevention purl.org/becyt/ford/2.10 [https] Pandemic Global health Infection control lcsh:QH301-705.5 Spectroscopy treatment nanotechnology NANOTECHNOLOGY General Medicine TREATMENT 021001 nanoscience & nanotechnology Computer Science Applications Nanomedicine 0210 nano-technology medicine.medical_specialty Context (language use) Catalysis Inorganic Chemistry 03 medical and health sciences Quality of life (healthcare) Acquired immunodeficiency syndrome (AIDS) medicine Humans Physical and Theoretical Chemistry Intensive care medicine Molecular Biology Acquired Immunodeficiency Syndrome business.industry Public health Organic Chemistry medicine.disease HIV infection PREVENTION Nanostructures 030104 developmental biology lcsh:Biology (General) lcsh:QD1-999 HIV INFECTION purl.org/becyt/ford/2 [https] NANOSYSTEMS business |
| Zdroj: | CONICET Digital (CONICET) Consejo Nacional de Investigaciones Científicas y Técnicas instacron:CONICET International Journal of Molecular Sciences, Vol 21, Iss 8647, p 8647 (2020) International Journal of Molecular Sciences |
| Popis: | Sexually-transmitted infections (STIs) are a global health concern worldwide as they cause acute diseases, infertility, and significant mortality. Among the bacterial, viral, and parasitic pathogens that can be sexually transmitted, human immunodeficiency virus (HIV) has caused one of the most important pandemic diseases, which is acquired immune deficiency syndrome (AIDS). 32.7 million people have died from AIDS-related illnesses since the start of the epidemic. Moreover, in 2019, 38 million people were living with HIV worldwide. The need to deal with this viral infection becomes more obvious, because it represents not only a problem for public health, but also a substantial economic problem. In this context, it is necessary to focus efforts on developing methods for prevention, detection and treatment of HIV infections that significantly reduce the number of newly infected people and provide a better quality of life for patients. For several decades, biomedical research has been developed allowing quick solutions through the contribution of effective tools. One of them is the use of polymers as vehicles, drug carrier agents, or as macromolecular prodrugs. Moreover, nanosystems (NSs) play an especially important role in the diagnosis, prevention, and therapy against HIV infection. The purpose of this work is to review recent research into diverse NSs as potential candidates for prevention and treatment of HIV infection. Firstly, this review highlights the advantages of using nanosized structures for these medical applications. Furthermore, we provide an overview of different types of NSs used for preventing or combating HIV infection. Then, we briefly evaluate the most recent developments associated with prevention and treatment alternatives. Additionally, the implications of using different NSs are also addressed. Fil: Macchione, Micaela Alejandra. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina Fil: Aristizabal, Dariana. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina Fil: Figueroa, Francisco Nicolas. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina Fil: Muñoz Fernández, María Ángeles. Instituto Investigación Sanitaria Gregorio Marañón; España Fil: Strumia, Miriam Cristina. Universidad Nacional de Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación y Desarrollo en Ingeniería de Procesos y Química Aplicada; Argentina |
| Databáze: | OpenAIRE |
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