Cardiac Involvement and Subsequent Death due to Extranodal NK/T Cell Cutaneous T-Cell Lymphoma: An Autopsy Case and Brief Review of the Literature
| Autor: | Nikolaos Goutas, Kalliroi Spanou, P Korkolopoulou, Konstantinos D. Katsos, Dimitrios Vlachodimitropoulos, Emmanouil I. Sakelliadis, Eleftheria Lakiotaki |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty Heart lymphoma medicine.medical_treatment T cell Autopsy Case Report Heart infiltration Sudden cardiac death Forensic medicine medicine RB1-214 Cause of death Chemotherapy Extranodal NK/T-cell lymphoma business.industry Cutaneous T-cell lymphoma Nasal type medicine.disease Lymphoma medicine.anatomical_structure business Infiltration (medical) |
| Zdroj: | Iranian Journal of Pathology Iranian Journal of Pathology, Vol 16, Iss 3, Pp 337-342 (2021) |
| ISSN: | 2345-3656 1735-5303 |
| Popis: | Cardiac tumors range from benign to high grade malignancies. The incidence of cardiac involvement either by primary, or secondary tumors during autopsy is reported to be extremely low. Extranodal NK/T-cell lymphoma (ENKTL), nasal type is an unusual type of lymphoma. The skin is the second most common site of involvement after the respiratory tract. We present a case of a 63-year-old male, who was recently diagnosed with ENKTL, nasal type, who received chemotherapy, and died without any evident cause. The corpse was referred for routine medicolegal examination. Macroscopical determination of the cause of death was not feasible and subsequent histopathological examination revealed heart infiltration by ENKTL that was found in vivo in cutaneous lesions. Similar infiltrations existed in the pancreatic tissue. To the best of our knowledge, myocardial infiltration of ENKTL, inducing severe myocardial lesions that eventually caused death, is rare, with limited cases reported in the literature. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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