RETINAL DETACHMENT AND RETROBULBAR CYSTS IN A LARGE COHORT OF OPTIC NERVE COLOBOMA
Autor: | Wai Ching Lam, Susan Blaser, Robert G. Devenyi, Peter J. Kertes, Chetan K. Patel, Yufeng N. Chen |
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Rok vydání: | 2018 |
Předmět: |
Male
medicine.medical_specialty Optic nerve coloboma genetic structures Optic Disk Fundus (eye) 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Risk Factors Ophthalmology Optic Nerve Diseases Orbital Diseases medicine Humans Retrospective Studies medicine.diagnostic_test Cysts business.industry Incidence Retinal Detachment Infant Retinal detachment Optic Nerve Magnetic resonance imaging Retinal Retrospective cohort study General Medicine medicine.disease eye diseases Indirect ophthalmoscopy Large cohort Coloboma chemistry Child Preschool 030221 ophthalmology & optometry Female sense organs business 030217 neurology & neurosurgery |
Zdroj: | Retina. 38:692-697 |
ISSN: | 0275-004X |
DOI: | 10.1097/iae.0000000000001594 |
Popis: | Purpose To examine the relationship between retinal detachment and retrobulbar cysts in patients with optic nerve coloboma (ONC) and Morning Glory syndrome (MGS). Methods Patients diagnosed with either ONC or MGS were identified through a search of the Sick Kids database. Seventy-one patients either agreed to come in for a B-scan or had an incidental orbital B-scan or magnetic resonance imaging or both. Eyes with orbital B-scan ultrasound and/or magnetic resonance imaging images were assessed independently by two ophthalmologists and a radiologist for the presence of retrobulbar cysts. Retinal detachment was identified clinically with either indirect ophthalmoscopy or from fundus photographs. Results Forty-five of 71 (63%) and 26/71 (37%) patients had ONC and MGS, respectively. Retinal detachment occurred significantly more often in eyes with MGS than with ONC (9/17 [53%] vs. 5/45 [11%], P = 0.03, respectively). Retrobulbar cysts were not detected more often in MGS than in ONC (11/45 [24%] vs. 7/26 [27%]; P = 1.0). Eyes with retrobulbar cysts were significantly more likely to be associated with retinal detachment than those without (7/18 [39%] vs. 7/53 [13%]; P = 0.04). Conclusion Retinal detachment occurs more frequently in MGS than in ONC in a cohort of patients referred to a specialist children's retinal service. Eyes with retrobulbar cysts are more likely to be associated with retinal detachment. |
Databáze: | OpenAIRE |
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