Copeptin concentration following cardiac surgery as a prognostic marker of postoperative acute kidney injury: a prospective cohort study
| Autor: | Shinya Yokoyama, Ryohei Fukuba, Tomoaki Hirose, Junichi Takemura, Keigo Yamashita, Takehisa Abe, Shun Hiraga, Kazuki Yamamoto, Yoshihiro Hayata, Shigeki Taniguchi, Rei Tonomura |
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| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
Vasopressin medicine.medical_specialty business.industry Acute kidney injury Central venous pressure medicine.disease Cardiac surgery Copeptin Internal medicine medicine Clinical endpoint Cardiology Biomarker (medicine) Original Article Prospective cohort study business |
| Zdroj: | J Thorac Dis |
| ISSN: | 2077-6624 2072-1439 |
| Popis: | BACKGROUND: Copeptin, the C-terminal portion of the arginine vasopressin precursor, is a novel candidate biomarker. This study investigated the prognostic value of copeptin levels following cardiac surgery for the occurrence of postoperative acute kidney injury. METHODS: We studied 23 patients who underwent cardiac surgery between January 2018 and December 2019. The primary endpoint was postoperative acute kidney injury onset. Copeptin levels were measured before, right after, and daily for 7 days. The patients were divided into two groups according to the copeptin levels: low (values |
| Databáze: | OpenAIRE |
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