Early electrophysiologic and anatomic alterations in cat ventricular muscle after coronary artery ligation
| Autor: | Kristina Epstein, Arthur L. Bassett, Samuel S. Wong, M. Nadji, Robert J. Myerburg, Henry Gelband, Azorides R. Morales, Alan M. Ezrin, Marion S. Gaide |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
medicine.medical_specialty
Physiology Myocardial Infarction Action Potentials Biochemistry Membrane Potentials Electrocardiography Internal medicine medicine Ventricular muscle Animals Ligation business.industry Heart Resting potential Coronary Vessels Artery ligation Electrophysiology Kinetics Cardiology Cats Action potential duration business Rate of rise Cellular necrosis |
| Zdroj: | Archives internationales de physiologie et de biochimie. 89(5) |
| ISSN: | 0003-9799 |
| Popis: | (2 figures)The effect of coronary artery ligation on electrophysiologic properties of cat ventricular muscle cells was studied. Depression of resting potential, action potential rate of rise and amplitude was observed in infarcted cells, 30 min to 5 days after ligation. Action potential duration was markedly shortened in acute stages (30–120 min) but gradually lengthened to above control by 48 h. Anatomic sequelae included oedema, loss of fibre striation and cellular necrosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|