MRI-defined White Matter Microstructural Alteration Associated with Soccer Heading Is More Extensive in Women than Men
| Autor: | Michael L. Lipton, Eva Catenaccio, Mimi Kim, Liane E. Hunter, Roman Fleysher, Richard B. Lipton, Naomi Lubin, Todd G. Rubin, Walter F. Stewart |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Heading (navigation) Adolescent Head (linguistics) Neuroimaging Brain tissue White matter Young Adult 03 medical and health sciences Sex Factors 0302 clinical medicine Soccer medicine Humans Radiology Nuclear Medicine and imaging Longitudinal Studies Prospective Studies business.industry 030229 sport sciences Anatomy Middle Aged Magnetic Resonance Imaging White Matter Cross-Sectional Studies Diffusion Tensor Imaging medicine.anatomical_structure Athletes Anisotropy Female business 030217 neurology & neurosurgery |
| Zdroj: | Radiology. 289:478-486 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/radiol.2018180217 |
| Popis: | Purpose To examine the role of sex in abnormal white matter microstructure after soccer heading as identified by using the diffusion-tensor imaging (DTI) metric fractional anisotropy (FA). Materials and Methods In this prospective cross-sectional study, 98 individuals who were enrolled in a larger prospective study of amateur soccer players (from 2013 to 2016) were matched 1:1 for age and history of soccer heading in the prior 12 months. Among the subjects, 49 men (mean age, 25.7 years; range, 18-50 years) and 49 women (mean age, 25.8 years; range, 18-50 years) with median total soccer headings per year of 487 and 469, respectively, underwent 3.0-T DTI. Images were registered to the Johns Hopkins University template. A voxelwise linear regression was fitted for FA with terms for the number of headings during the previous 12 months and its interaction with sex after controlling for the following potential confounders: age, years of education, number of lifetime concussions, and handedness. In the resulting statistical maps, P.01 indicated a statistically significant difference, with a threshold cluster size larger than 100 mm |
| Databáze: | OpenAIRE |
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