Effect of secretin upon the levels of pancreatic enzymes in blood serum
| Autor: | E. Ruffilli, Luisa Zoni, P. Malaguti, Carlo Lesi, A. Scandellari, C. Matacena |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Adult
Male medicine.medical_specialty Glycoside Hydrolases medicine.medical_treatment Clinical Biochemistry Secretin Blood serum Internal medicine medicine Humans Intubation Trypsin Lipase Pancreas Cholecystokinin chemistry.chemical_classification biology business.industry General Medicine Middle Aged medicine.disease Enzyme Endocrinology Pancreatitis chemistry Chronic Disease biology.protein Female business Isoamylase medicine.drug |
| Zdroj: | Clinical Biochemistry. 18:317-321 |
| ISSN: | 0009-9120 |
| DOI: | 10.1016/s0009-9120(85)80040-0 |
| Popis: | We have evaluated the serum changes of trypsin, pancreatic isoamylase and lipase, after rapid infusion of secretin, in 45 patients with chronic pancreatitis compared with 35 healthy control subjects. On the basis of duodenal intubation results, chronic pancreatitis patients were divided into two subgroups at different levels of functional impairment. Using the peak activities of the enzymes we have been able to separate the two chronic pancreatitis subgroups by statistical difference; only trypsin distinguishes healthy control subjects from mild to moderate chronic pancreatitis. Therefore, we propose to put into clinical practice this serum provocative test to evaluate the functional damage of an established chronic pancreatitis. |
| Databáze: | OpenAIRE |
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