Alpha-I-antitrypsin (Pi) phenotypes in Lyon, France: departure from Hardy-Weinberg equilibrium

Autor:	H. Hugh Fudenberg, Chapuis-Cellier C, Philippe Arnaud, Janardan P. Pandey, Vittoz P, Creyssel R
Rok vydání:	2008
Předmět:	Adult Genetics Heterozygote education.field_of_study Adolescent Homozygote Population Alpha (ethology) Pi phenotypes Middle Aged Biology Hardy–Weinberg principle Phenotype Gene Frequency alpha 1-Antitrypsin Humans France education Genetics (clinical)
Zdroj:	Clinical Genetics. 12:77-79
ISSN:	1399-0004 0009-9163
DOI:	10.1111/j.1399-0004.1977.tb00905.x
Popis:	The validity of the Hardy-Weinberg equilibrium for Pi phenotypes was tested in a population of 1,653 randomly selected, healthy blood donors in Lyon, France. A significant departure from the equilibrium was found, with an excess of FF and SS homozygotes and a deficiency of FM heterozygotes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770e49bf77763941f3c7116656a6d0f6 https://doi.org/10.1111/j.1399-0004.1977.tb00905.x Zobrazit plný text záznamu Plný text