Distinguishing features of acute Vogt-Koyanagi-Harada disease and acute central serous chorioretinopathy on optical coherence tomography angiography and en face optical coherence tomography imaging
| Autor: | Aman Sharma, Aniruddha Agarwal, Vishali Gupta, Sarakshi Mahajan, Mangat R Dogra, Reema Bansal, Ramandeep Singh, Kanika Aggarwal, Ankit Deokar |
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| Rok vydání: | 2016 |
| Předmět: |
Vogt–Koyanagi–Harada disease
medicine.medical_specialty Indocyanine green angiography Central serous chorioretinopathy Ischemia Vogt-Koyanagi-Harada syndrome 03 medical and health sciences 0302 clinical medicine Optical coherence tomography Acute central serous chorioretinopathy Ophthalmology Multimodal imaging medicine EDI-OCT Original Research medicine.diagnostic_test business.industry Optical coherence tomography angiography medicine.disease Fluorescein angiography eye diseases Infectious Diseases 030221 ophthalmology & optometry Radiology business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Ophthalmic Inflammation and Infection |
| ISSN: | 1869-5760 |
| Popis: | Background The aim of this study is to determine the differences in optical coherence tomography angiography (OCTA) features of acute Vogt-Koyanagi-Harada disease (VKH) and acute central serous chorioretinopathy (CSC). Clinical and imaging data of patients with acute CSC and VKH in a tertiary-care institute were analyzed. Multimodal imaging including fluorescein angiography, indocyanine green angiography (ICGA), and enhanced-depth imaging OCT were performed. OCTA images were analyzed for alterations in retinochoroidal microvasculature. Results Thirty-four eyes (24 patients; 10 with VKH and 14 with CSC) were included. OCTA en face images showed apparent areas of choriocapillaris flow void due to shadowing effect from overlying subretinal fluid and pigment epithelial detachment in CSC. However, eyes with VKH showed presence of true choriocapillaris flow void on OCTA that corresponded to choriocapillaris ischemia on ICGA. Conclusions OCTA is a useful tool to assess choriocapillaris ischemia in VKH and is helpful to differentiate it from CSC in the acute stage. |
| Databáze: | OpenAIRE |
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