Effect of statins and white blood cell count on mortality in patients with ischemic left ventricular dysfunction undergoing percutaneous coronary intervention
| Autor: | Michael J. Cowley, Robert E. Johnson, Evelyne Goudreau, Robert E. Martin, Walter N. Malloy, J B S Michael Lipinski, George W. Vetrovec |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Acute coronary syndrome medicine.medical_specialty medicine.medical_treatment Population Clinical Investigations Myocardial Ischemia Coronary Angiography Coronary artery disease Leukocyte Count Ventricular Dysfunction Left hemic and lymphatic diseases Internal medicine White blood cell medicine Humans Angioplasty Balloon Coronary education Proportional Hazards Models Retrospective Studies education.field_of_study Ejection fraction business.industry Percutaneous coronary intervention General Medicine Odds ratio Middle Aged Prognosis medicine.disease Survival Analysis medicine.anatomical_structure Conventional PCI Cardiology Female Hydroxymethylglutaryl-CoA Reductase Inhibitors Cardiology and Cardiovascular Medicine business circulatory and respiratory physiology |
| Zdroj: | Clinical Cardiology. 29:36-41 |
| ISSN: | 1932-8737 0160-9289 |
| Popis: | Background: While morbidity and mortality were shown to be increased in the setting of an elevated white blood cell (WBC) count for patients with acute coronary syndrome, the impact of statin therapy on mortality for patients with an elevated WBC count is unknown in high‐risk patients with coronary artery disease. Hypothesis: The goal of this study was to determine whether statin therapy improved survival in patients with elevated WBC count undergoing percutaneous coronary intervention (PCI) with preexisting left ventricular (LV) dysfunction, a population at high risk for adverse outcomes. Methods: We retrospectively evaluated consecutive patient procedures performed at our institution from 1996 through 1999. Patients had a technically adequate angiographic left ventriculogram with a calculated ejection fraction(EF) ≤ 50%. Patients with prior coronary artery bypass graft were excluded. Mortality data were retrieved using the U.S. Social Security Death Index. Follow‐up ranged from 3.5 to 6.5 years. Means are provided with ± standard deviation, and p values |
| Databáze: | OpenAIRE |
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