Determination of periodontopathogens in patients with cri du chat syndrome

Autor: Rosa-María Yáñez-Vico, Enrique Solano-Reina, Sofía Ballesta-Mudarra, Guillermo Machuca-Portillo, Evelio Perea-Pérez, Ángela Rodríguez-Caballero, Daniel Torres-Lagares
Přispěvatelé: Universidad de Sevilla. Departamento de Estomatología, Universidad de Sevilla. Departamento de Microbiología
Rok vydání: 2013
Předmět:
Zdroj: idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Medicina Oral, Patología Oral y Cirugía Bucal
Ballesta, Sofía ; Machuca Portillo, Guillermo ; Torres Lagares, Daniel ; Rodríguez Caballero, Ángela ; Yáñez Vico, Rosa María ; Solano Reina, Enrique ; Perea Pérez, Evelio J.. Determination of periodontopathogens in patients with Cri du chat syndrome. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2013, Vol. 18, No. 6: 883-887
RODERIC. Repositorio Institucional de la Universitat de Valéncia
ISSN: 1698-6946
Popis: Objectives: Cri du chat syndrome is a genetic alteration associated with some oral pathologies. However, it has not been described previously any clinical relationship between the periodontal disease and the syndrome. The purpose of this comparative study was to compare periodontopathogenic flora in a group with Cri du chat syndrome and another without the síndrome, to assess a potential microbiological predisposition to suffer a periodontitis. Study Design: The study compared nineteen subjects with Cri du chat Syndrome with a control group of nineteen patients without it. All patients were clinically evaluated by periodontal probing, valuing the pocket depth, the clinical attachmente level and bleeding on probing. There were no significant differences between both groups. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola were detected by multiplex-PCR using 16S rDNA (microIDENT). Results: When A. actinomycetemcomitans, P. gingivalis, P. intermedia and T. denticola were compared, no statistically significant differences were found between the two groups (p>0.05). The value of T. forsythia was significantly higher for Cri du chat syndrome (31.6%) than for the control group (5.3%). The odds ratio for T. forsythia was 8.3. Conclusions: In the present study T. forsythia is associated with Cri du chat syndrome subjects and not with healthy subjects. Department of Stomatology (CTS-113) (CTS-353) School of Medicine (CTS-210) Instituto de Investigación de la Universidad de Sevilla (España)
Databáze: OpenAIRE