Monetary costs and hospital burden associated with the management of invasive fungal infections in Mexico: a multicenter study

Autor: Alexandra Martin-Onraet, Adrián Camacho-Ortiz, Dora E Corzo-Leon, Hiram Villanueva-Lozano, Norma E. Rivera-Martinez, Diana Perales-Martínez
Rok vydání: 2018
Předmět:
0301 basic medicine
Male
Antifungal Agents
Time Factors
lcsh:QR1-502
lcsh:Microbiology
Fungal infections
Cost of Illness
Economic cost
Antifungal therapy
Mortality rate
Incidence (epidemiology)
Incidence
Liver Diseases
Acute kidney injury
Disease Management
Acute Kidney Injury
Middle Aged
Hospitalization
Intensive Care Units
Infectious Diseases
Female
medicine.symptom
Microbiology (medical)
Adult
medicine.medical_specialty
Tuberculosis
Cost
030106 microbiology
Incidence rate
Asymptomatic
Statistics
Nonparametric
lcsh:Infectious and parasitic diseases
03 medical and health sciences
medicine
Humans
lcsh:RC109-216
Adverse effect
Mexico
Retrospective Studies
business.industry
medicine.disease
Survival Analysis
Cross-Sectional Studies
Multicenter study
Emergency medicine
Multivariate Analysis
business
Invasive Fungal Infections
Zdroj: Brazilian Journal of Infectious Diseases, Vol 22, Iss 5, Pp 360-370
Brazilian Journal of Infectious Diseases, Vol 22, Iss 5, Pp 360-370 (2018)
Brazilian Journal of Infectious Diseases v.22 n.5 2018
Brazilian Journal of Infectious Diseases
Brazilian Society of Infectious Diseases (BSID)
instacron:BSID
Brazilian Journal of Infectious Diseases, Volume: 22, Issue: 5, Pages: 360-370, Published: OCT 2018
ISSN: 1678-4391
Popis: Background: Invasive fungal infections (IFIs) affect >1.5 million people per year. Nevertheless, IFIs are usually neglected and underdiagnosed. IFIs should be considered as a public-health problem and major actions should be taken to tackle them and their associated costs. Aim To report the incidence of IFIs in four Mexican hospitals, to describe the economic cost associated with IFIs therapy and the impact of adverse events such as acute kidney injury (AKI), liver damage (LD), and ICU stay. Methods: This was a retrospective, transversal study carried-out in four Mexican hospitals. All IFIs occurring during 2016 were included. Incidence rates and estimation of antifungal therapy's expenditure for one year were calculated. Adjustments for costs of AKI were done. An analysis of factors associated with death, AKI, and LD was performed. Results: Two-hundred thirty-eight cases were included. Among all cases, AKI was diagnosed in 16%, LD in 25%, 35% required ICU stay, with a 23% overall mortality rate. AKI and LD showed higher mortality rates (39% vs 9% and 44% vs 18%, respectively, p
Databáze: OpenAIRE
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