Early Detection of Asymptomatic Pulmonary Melanoma Metastases by RoutineChest Radiographs Is Not Associated With Improved Survival
| Autor: | William B. Goggins, Arthur J. Sober, Julie E. Fullerton, Daniel I. Rosenthal, Myra Feldman, Hensin Tsao |
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| Rok vydání: | 2004 |
| Předmět: |
Thorax
medicine.medical_specialty Lung Neoplasms Skin Neoplasms Population Dermatology Asymptomatic Metastasis medicine Humans education Melanoma education.field_of_study Lung business.industry Medical record Respiratory disease General Medicine medicine.disease Survival Rate medicine.anatomical_structure Radiography Thoracic Radiology medicine.symptom business |
| Zdroj: | Archives of Dermatology. 140 |
| ISSN: | 0003-987X |
| Popis: | Objective To determine if earlier detection of pulmonary metastasis by routinechest radiography (CR) is associated with a prolonged survival. Design A computer-assisted search of all CR reports on patients with melanomabetween 1990 and 1994 at the Massachusetts General Hospital, Boston. Positiveor suspicious findings for pulmonary metastasis were further pursued throughreview of medical records and tumor registry files. Setting and Patients A hospital-based population of patients with melanoma undergoing routineCR at Massachusetts General Hospital. Results Overall, of 994 patients, 75 were identified as having pulmonary metastasesby CR (1937 total chest radiographs). In addition, there were 63 patientswith suspicious findings that were later shown to be false positive. Chestradiographs provided the initial evidence of metastases in 41 asymptomaticindividuals. Thirty-four patients had known melanoma metastases to other sitesat the time of the first abnormal chest radiograph. Survival after identificationof pulmonary metastasis did not differ significantly between the 2 groups. Conclusions In this study, there was no evidence to support the notion that earlierdetection of pulmonary metastasis in otherwise asymptomatic individuals confersa survival advantage in an unselected melanoma population. |
| Databáze: | OpenAIRE |
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