| Autor: |
Sung-Han Yoon, Moody Makar, Saibal Kar, Keita Koseki, Luke Oakley, Navjot Sekhon, Dhairya Patel, Tarun Chakravarty, Mamoo Nakamura, Michele Hamilton, Jignesh K. Patel, Siddharth Singh, Skaf Sabah, Robert J. Siegel, Jeroen J. Bax, Raj R. Makkar |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
The American journal of cardiology. 182 |
| ISSN: |
1879-1913 |
| Popis: |
Assessment of left ventricular (LV) systolic function is essential in patient selection for transcatheter edge-to-edge repair (TEER) in secondary mitral regurgitation (MR). Although LV ejection fraction (EF) is mostly used for assessing LV function, it represents the change of LV chamber size, but not myocardial contractility. LV global longitudinal strain (GLS) provides an alternative to assess LV systolic function in patients with secondary MR. This study included 380 patients with secondary MR (mean age 71.0 ± 13.0 years; 61.1% male) who underwent TEER. Patients were dichotomized based on baseline LV GLS (more impaired GLS [7.0%] vs less impaired GLS [≥7%]) based on existing literature. The primary outcome was all-cause mortality, whereas the secondary outcome was the composite end point of all-cause mortality and heart failure hospitalization. The mean LV GLS was 8.1 ± 3.8%, and 162 patients had GLS7%. Patients with more impaired GLS (7%) were more likely to be male (68.5% vs 55.5%; p = 0.01) and have larger LV end-diastolic volume (110.5 ± 36.5 ml/m |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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Full Text from ScienceDirect