Central nervous system activity of terpenoids from marine sponge
| Autor: | C. Circosta, Francesco Occhiuto, S. De Rosa, R. De Pasquale, S. De Stefano |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
medicine.drug_class
Stereochemistry Analgesic Central nervous system Drug Evaluation Preclinical Cnidaria Mice terpenoids medicine Animals analgesic activity Benzoquinol marine sponge Pharmacology Analgesics biology Traditional medicine Low toxicity Muscle Relaxants Central Terpenes Muscle relaxant Biological activity biology.organism_classification Terpenoid Sponge medicine.anatomical_structure Central Nervous System Agents |
| Zdroj: | Pharmacological Research Communications. 20:23-26 |
| ISSN: | 0031-6989 |
| DOI: | 10.1016/s0031-6989(88)80833-6 |
| Popis: | Summary Some terpenoids extracted from marine sponge: triacetylated disidein, 2-tetraprenyl benzoquinol and 4 hydroxy-3-tetraprenylbenzoic acid 2-polyprenyl benzoquinols, avarol and furospongin-1 were tested by multidimensional Irwin screening and with some tests for analgesic and muscle relaxant activity. The three prenylhydroquinols derivatives and avarol show a good analgesic activity and low toxicity. |
| Databáze: | OpenAIRE |
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