A refined palate: Bacterial consumption of host glycans in the gut

Autor:	Kristen A. Earle, Justin L. Sonnenburg, Audrey Southwick, Angela Marcobal
Rok vydání:	2013
Předmět:	Glycan Bacteria biology Human intestine Host (biology) Mucin Gut flora biology.organism_classification Special Issue - Reviews on Glycan-Mediated Host-Microbe Interactions Biochemistry Mucus Microbiology Intestines Polysaccharides biology.protein Humans Microbiome Intestinal Mucosa
Zdroj:	Glycobiology. 23:1038-1046
ISSN:	1460-2423 0959-6658
DOI:	10.1093/glycob/cwt040
Popis:	The human intestine houses a dense microbial ecosystem in which the struggle for nutrients creates a continual and dynamic selective force. Host-produced mucus glycans provide a ubiquitous source of carbon and energy for microbial species. Not surprisingly, many gut resident bacteria have become highly adapted to efficiently consume numerous distinct structures present in host glycans. We propose that sophistication in mucus consumption is a trait most likely to be found in gut residents that have co-evolved with hosts, microbes that have adapted to the complexity associated with the host glycan landscape.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76eba409c12847dfb153c217635dc37c https://doi.org/10.1093/glycob/cwt040 Zobrazit plný text záznamu