Efficacy of a twice-daily, 3-step, over-the-counter skincare regimen for the treatment of acne vulgaris
| Autor: | Katie Rodan, Kathy Fields, T. Falla |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty acne treatment business.industry Scars Dermatology Acne treatment medicine.disease 030207 dermatology & venereal diseases 03 medical and health sciences Regimen 030104 developmental biology 0302 clinical medicine Clinical Cosmetic and Investigational Dermatology medicine Over-the-counter medicine.symptom business acne over-the-counter Acne Original Research skincare regimen |
| Zdroj: | Clinical, Cosmetic and Investigational Dermatology |
| ISSN: | 1178-7015 |
| DOI: | 10.2147/ccid.s125438 |
| Popis: | Katie Rodan,Kathy Fields,Timothy J Falla Rodan + Fields, San Francisco, CA,USA Background: Acne vulgaris (acne) is the most common skin disorder producing physical and emotional scars that can persist for years. An estimated 83% of acne sufferers self-treat, but there is lack of studies documenting the effectiveness of over-the-counter (OTC) acne treatment products.Objective: This study was conducted to determine the effectiveness of an OTC, 3-step, anti-acne skincare regimen in treating acne and improving the appearance of red/inflamed facial skin.Methods: This 6-week, open-label clinical study included both genders aged between 12 and 35 years with mild-to-moderate acne. All subjects were required to have an acne score of 1–3 (Cook’s acne grading scale: 0=clear to 7=very severe) and a moderate redness score of ≥2 (0=none and 4=severe). Subjects completed a 3-step facial treatment regimen every morning and evening using an OTC cleanser, toner, and acne treatment. Evaluations for effectiveness and safety were done at baseline and weeks 2, 4, and 6 using digital photographs (Visia-CR® digital imaging system) of the face and analyzed using Image-Pro® software for the grading of acne, red/inflamed skin, and the number and type of lesions.Results: Thirty subjects (12 males and 18 females) were enrolled (mean age of 19 years; range 12–34 years). This skincare regimen resulted in statistically significant improvements in acne grading scores after 2 weeks of use, with mean scores continuing to improve after 4 and 6 weeks of use (P |
| Databáze: | OpenAIRE |
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